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Interventional neuroendocrinology is a relatively new concept. It is championed by Dr Mark Gordon. He promotes proactive monitoring and replacement of multiple hormones as needed to optimal levels. Dr Gordon elucidates his approach and clarifies his issues with the current standard of care and the use of standard reference ranges.

In this Episode You Will Learn:

Dr Gordon introduces the concept of “neurosteroids” which are hormones that are made by glial cells – support cells – in the brain. Hormones like Growth Hormone in Insulin Like Growth factor protect the brain and can be given or stimulated to create supportive neurochemistry and aid against brain damage.

The Blood-Brain-Barrier – which protects the brain from things that are running around in the rest of the body – can get leaky after a head injury. This allows things that aren’t normally given access to the brain to get access. White blood cells among other things from the rest of the body get into the brain and initiate an autoimmune response (e.g antibody against pituitary and hypothalamus) and set off a cascade of harmful reactions.

We discuss what Dr Gordon means by “the neuropermissive environment” which is a fascinating idea of giving the body all thing things it needs to heal the brain.

Dr Gordon notes the importance of zinc in down regulating the production of harmful products in Alzheimer’s and explains this process. He also discusses why aluminum is thought to a contributor to developing Alzheimer’s.

Long discussion about inflammation and oxidative stress in the brain and the use of N-acetyl cysteine and mixed tocopherols (E vitamins) that slow down inflammation.

Extensive discussion about thyroid hormone and the brain and nutrients and thyroid hormone’s role in the “neuropermissive” environment.

Conversation about whether or not there is a role for progesterone in men with brain damage.

Dr Gordon’s tells us about his work with brain injury and those who have served in the military.

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